Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
储存条件
-20 °C,-80 °C
储存方法
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Enables adrenomedullin binding activity, adrenomedullin receptor activity, and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway, cellular response to sucrose stimulus, and receptor internalization. Located in endoplasmic reticulum, endosome, and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. [provided by Alliance of Genome Resources, Apr 2022]
分子量
predicted molecular mass of 39.9 kDa after removal of the signal peptide. The apparent molecular mass of CGRPR-hFc is 35-70 kDa due to glycosylation.