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Calcitonin Receptor Protein (CALCR)

CALCR 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538150
发货至: 中国
  • 抗原 See all Calcitonin Receptor (CALCR) 蛋白
    Calcitonin Receptor (CALCR)
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 3
    • 1
    • 1
    资源
    • 3
    • 2
    Mammalian Cells
    原理
    Human CALCR full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product CALCR 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    Calcitonin Receptor (CALCR)
    别名
    CALCR (CALCR 产品)
    别名
    CALCR Protein, si:ch211-77k19.2 Protein, calcr Protein, CRT Protein, CT-R Protein, CTR Protein, CTR1 Protein, Clr Protein, Ct-R Protein, calcitonin receptor Protein, CALCR Protein, calcr Protein, Calcr Protein
    背景
    This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
    分子量
    The human full length CALCR protein has a MW of 55.3kDa
    UniProt
    P30988
    途径
    cAMP Metabolic Process
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