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ABCG1 蛋白

ABCG1 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538140
发货至: 中国
  • 抗原 See all ABCG1 蛋白
    ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 6
    • 2
    资源
    • 2
    • 2
    • 2
    • 1
    • 1
    Mammalian Cells
    原理
    Human ABCG1 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product ABCG1 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))
    别名
    ABCG1 (ABCG1 产品)
    别名
    ABCG1 Protein, zgc:162197 Protein, ABC8 Protein, WHITE1 Protein, AW413978 Protein, Abc8 Protein, White Protein, ATP binding cassette subfamily G member 1 Protein, ATP-binding cassette, sub-family G (WHITE), member 1 Protein, ABCG1 Protein, abcg1 Protein, Abcg1 Protein
    背景
    The protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types
    分子量
    The human full length ABCG1 protein has a MW of 75.6 kDa
    UniProt
    P45844
    途径
    Lipid Metabolism
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