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- 抗原 See all ABCG1 蛋白
- ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human ABCG1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 1-678) protein (GST tag)
ABCG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 21-130) protein (GST tag)ABCG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)ABCG1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))
- 别名
- ABCG1 (ABCG1 产品)
- 别名
- ABCG1 Protein, zgc:162197 Protein, ABC8 Protein, WHITE1 Protein, AW413978 Protein, Abc8 Protein, White Protein, ATP binding cassette subfamily G member 1 Protein, ATP-binding cassette, sub-family G (WHITE), member 1 Protein, ABCG1 Protein, abcg1 Protein, Abcg1 Protein
- 背景
- The protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types
- 分子量
- The human full length ABCG1 protein has a MW of 75.6 kDa
- UniProt
- P45844
- 途径
- Lipid Metabolism
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