AVPR1B 蛋白
AVPR1B
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all AVPR1B 蛋白
- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human V1BR full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product AVPR1B 蛋白
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Arginine Vasopressin Receptor 1B (AVPR1B) (AA 343-425), (partial) protein (His tag)
AVPR1B 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
- 别名
- V1BR (AVPR1B 产品)
- 别名
- LOC443050 Protein, AVPR1B Protein, si:ch211-125a15.3 Protein, AVPR3 Protein, V3/V1b Protein, VIBR Protein, VPR3 Protein, arginine vasopressin receptor 1B Protein, arginine vasopressin receptor 1Ab Protein, AVPR1B Protein, avpr1ab Protein, Avpr1b Protein
- 背景
- The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length V1BR protein has a MW of 47kDa
- UniProt
- P47901
- 途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
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