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APOH Protein (AA 20-345) (His tag)

APOH 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7538136
发货至: 中国
  • 抗原 See all APOH 蛋白
    APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
    蛋白类型
    Recombinant
    产品特性
    AA 20-345
    宿主
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    资源
    • 8
    • 7
    • 4
    • 2
    • 1
    Mammalian Cells
    标记
    This APOH protein is labelled with His tag.
    原理
    Recombinant human APOH Protein with C-terminal 6xHis tag
    特异性
    APOH (Gly20-Cys345) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product APOH 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
    别名
    APOH (APOH 产品)
    别名
    B2G1 Protein, B2GP1 Protein, BG Protein, BETA2 Protein, BHF-1 Protein, MODY6 Protein, NEUROD Protein, bHLHa3 Protein, apoh Protein, APOH Protein, B2GPI Protein, beta-2-GPI Protein, beta2-GPI Protein, LOC100227913 Protein, apolipoprotein H Protein, neuronal differentiation 1 Protein, APOH Protein, NEUROD1 Protein, apoh Protein, Apoh Protein
    背景
    Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019]
    分子量
    predicted molecular mass of 37.1 kDa after removal of the signal peptide. The apparent molecular mass of APOH-His is 35-70 kDa due to glycosylation.
    UniProt
    P02749
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