ADRB3 蛋白
ADRB3
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all ADRB3 蛋白
- ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human ADRB3 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product ADRB3 蛋白
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Adrenergic, beta-3-, Receptor (ADRB3) (AA 1-408) protein (GST tag)
ADRB3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
- 别名
- ADRB3 (ADRB3 产品)
- 别名
- BETA3AR Protein, Adrb-3 Protein, ADRB Protein, BAR3 Protein, B3AR Protein, GPCR Protein, im:7154935 Protein, si:ch211-215f19.1 Protein, zgc:194843 Protein, zgc:194852 Protein, adrenoceptor beta 3 Protein, adrenergic receptor, beta 3 Protein, adrenoceptor beta 3a Protein, adrenoceptor beta 3b Protein, ADRB3 Protein, Adrb3 Protein, adrb3a Protein, adrb3b Protein
- 背景
- The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]
- 分子量
- The human full length ADRB3 protein has a MW of 43.5kDa
- UniProt
- P13945
- 途径
- cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation
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