beta 2 Adrenergic Receptor 蛋白
ADRB2
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
-
- 抗原 See all beta 2 Adrenergic Receptor (ADRB2) 蛋白
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
- 蛋白类型
- Synthetic Nanodisc
-
宿主
- 人
-
资源
- Mammalian Cells
- 原理
- Human ADRB2 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product ADRB2 蛋白
-
Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 1-413) protein (GST tag)
ADRB2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
-
- 说明
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
-
- 抗原
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
- 别名
- ADRB2 (ADRB2 产品)
- 别名
- zgc:162188 Protein, adrb2 Protein, Adrb-2 Protein, Badm Protein, Gpcr7 Protein, ADRB2R Protein, ADRBR Protein, B2AR Protein, BAR Protein, BETA2AR Protein, adrenoceptor beta 2 Protein, adrenoceptor beta 2, surface b Protein, beta2-adrenergic receptor Protein, adrenergic receptor, beta 2 Protein, ADRB2 Protein, adrb2b Protein, LOC100136153 Protein, Adrb2 Protein
- 背景
- This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]
- 分子量
- The human full length ADRB2 protein has a MW of 46.5kDa
- UniProt
- P07550
- 途径
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
-
You are here:
