-
- 抗原 See all ADRB1 蛋白
- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
- 蛋白类型
- Synthetic Nanodisc
-
宿主
- 人
-
资源
- Mammalian Cells
- 原理
- Human ADRB1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
-
Adrenergic, beta-1-, Receptor (ADRB1) (AA 378-477) protein (His tag)
ADRB1 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
-
- 说明
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
-
- 抗原
- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
- 别名
- ADRB1 (ADRB1 产品)
- 别名
- ADRB1R Protein, B1AR Protein, BETA1AR Protein, RHR Protein, RATB1AR Protein, X-Beta1AR Protein, BAR1 Protein, zgc:194728 Protein, zgc:194731 Protein, ADRB1 Protein, Adrb-1 Protein, beta-AR Protein, adrenoceptor beta 1 Protein, adrenoceptor beta 1 L homeolog Protein, adrenergic, beta-1-, receptor Protein, adrenergic receptor, beta 1 Protein, ADRB1 Protein, Adrb1 Protein, adrb1.L Protein, adrb1 Protein
- 背景
- The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
- 分子量
- The human full length ADRB1 protein has a MW of 51.2 kDa
- UniProt
- P08588
- 途径
- cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation
-
You are here:
