Adenosine A3 Receptor Protein (ADORA3)
ADORA3
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all Adenosine A3 Receptor (ADORA3) 蛋白
- Adenosine A3 Receptor (ADORA3)
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human AA3R full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product ADORA3 蛋白
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Adenosine A3 Receptor (ADORA3) (AA 121-225) protein (GST tag)
ADORA3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Adenosine A3 Receptor (ADORA3)
- 别名
- AA3R (ADORA3 产品)
- 别名
- A3AR Protein, AD026 Protein, bA552M11.5 Protein, ADORA3 Protein, 1700001D09Rik Protein, 4930578J19Rik Protein, A3R Protein, AA3R Protein, ARA3 Protein, Gpcr2 Protein, adenosine A3 receptor Protein, adenosine receptor A3 Protein, ADORA3 Protein, Adora3 Protein, LOC100603318 Protein
- 背景
- This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014]
- 分子量
- The human full length AA3R protein has a MW of 36.2kDa
- UniProt
- P0DMS8
- 途径
- Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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