ADORA1 蛋白
ADORA1
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all ADORA1 蛋白
- ADORA1 (Adenosine A1 Receptor (ADORA1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human AA1R full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product ADORA1 蛋白
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- ADORA1 (Adenosine A1 Receptor (ADORA1))
- 别名
- AA1R (ADORA1 产品)
- 别名
- adora1-A Protein, a1R Protein, ADORA1 Protein, LOC606743 Protein, LOC100222054 Protein, RDC7 Protein, A1-AR Protein, A1AR Protein, A1R Protein, AA1R Protein, AI848715 Protein, BB176431 Protein, Ri Protein, adenosine A1 receptor L homeolog Protein, adenosine A1 receptor Protein, adenosine receptor A1 Protein, adora1.L Protein, ADORA1 Protein, adora1 Protein, LOC100222054 Protein, Adora1 Protein
- 背景
- The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length AA1R protein has a MW of 36.5kDa
- UniProt
- P30542
- 途径
- EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Synaptic Membrane
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