HTR7 蛋白
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- 抗原 See all HTR7 蛋白
- HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human 5HT7R full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product HTR7 蛋白
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))
- 别名
- 5HT7R (HTR7 产品)
- 别名
- 5-HT7 Protein, 5-HT-dro Protein, 5-HT-dro1 Protein, 5-HT7Dro Protein, 5-HT[7]Dro Protein, 5-HT[[7Dro]] Protein, 5-HT[[7]] Protein, 5-HT[[7]]Dro Protein, 5-HT[[dro1]] Protein, 5-HTdro1 Protein, 5HT-7 Protein, 5HT-R1 Protein, 5HT-dro Protein, 5HT-dro1 Protein, 5HT[[7Dro]] Protein, 5htdror Protein, CG12073 Protein, DRO1 Protein, Dm5HTdro1 Protein, Dmel\\CG12073 Protein, 5Ht7 Protein, 5HT7 Protein, htr7-A Protein, 5-hydroxytryptamine receptor 7 Protein, 5-hydroxytryptamine (serotonin) receptor 7 Protein, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled Protein, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled L homeolog Protein, HTR7 Protein, 5-HT7 Protein, LOC752003 Protein, Htr7 Protein, htr7.L Protein
- 背景
- The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
- 分子量
- The human full length 5HT7R protein has a MW of 53.6kDa
- UniProt
- P34969
- 途径
- JAK/STAT Signaling
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