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s100a4 蛋白

S100A4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE.
产品编号 ABIN7535876
发货至: 中国
  • 抗原 See all s100a4 (S100A4) 蛋白
    s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 5
    • 3
    • 3
    • 1
    资源
    • 13
    • 5
    • 3
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human S100-A4 Protein
    序列
    ACPLEKALDV MVSTFHKYSG KEGDKFKLNK SELKELLTRE LPSFLGKRTD EAAFQKLMSN LDSNRDNEVD FQEYCVFLSC IAMMCNEFFE GFPDKQPRKK
    特异性
    Ala2-Lys101
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    <0.1EU/μg
    Top Product
    Discover our top product S100A4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
    别名
    S100-A4 (S100A4 产品)
    别名
    18A2 Protein, 42A Protein, CAPL Protein, FSP1 Protein, MTS1 Protein, P9KA Protein, PEL98 Protein, 42a Protein, Capl Protein, FSp1 Protein, Mts1 Protein, PeL98 Protein, metastasin Protein, pk9a Protein, S100A4 Protein, P9ka Protein, RNP9KA Protein, S100 calcium binding protein A4 Protein, S100 calcium-binding protein A4 Protein, S100A4 Protein, S100a4 Protein
    背景

    Description: S100A4 belongs to the family of small calcium-binding S100 proteins containing two EF-hand calcium-binding motifs. In humans at least 20 S100 family members that are distributed tissue specifically have been identified, and are involved in a number of cellular processes as transducers of calcium signal. S100A4 is a symmetric homodimer, and undergoes a relatively large conformational change upon the typical EF-hand binding calcium, which is necessary for S100A4 to interact with its protein targets and generate biological effects. It can bind the already known targets p53, F-actin, liprin β, myosin heavy chain II, and prevent their phosphorylation and multimerization. It has been demonstrated that S100A4 is directly involved in tumor metastasis including cell motility, invasion, apoptosis, angiogenesis and differentiation, and appears to be a metastasis factor and a molecular marker for clinical prognosis. Multiple alternatively spliced variants encoding the same protein have been identified.

    Name: 18A2,42A,CAPL,FSP1,MTS1,P9KA,PEL98,S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98, protein S100-A4

    基因ID
    6275
    UniProt
    P26447
    途径
    S100 Proteins
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