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Retinoblastoma Binding Protein 4 Protein (RBBP4)

RBBP4 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 92 % by SDS-PAGE. Active
产品编号 ABIN7520441
发货至: 中国
  • 抗原 See all Retinoblastoma Binding Protein 4 (RBBP4) 蛋白
    Retinoblastoma Binding Protein 4 (RBBP4)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 6
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    Baculovirus infected Insect Cells
    原理
    Active Recombinant Human RBBP-4 Protein
    序列
    MADKEAAFDD AVEERVINEE YKIWKKNTPF LYDLVMTHAL EWPSLTAQWL PDVTRPEGKD FSIHRLVLGT HTSDEQNHLV IASVQLPNDD AQFDASHYDS EKGEFGGFGS VSGKIEIEIK INHEGEVNRA RYMPQNPCII ATKTPSSDVL VFDYTKHPSK PDPSGECNPD LRLRGHQKEG YGLSWNPNLS GHLLSASDDH TICLWDISAV PKEGKVVDAK TIFTGHTAVV EDVSWHLLHE SLFGSVADDQ KLMIWDTRSN NTSKPSHSVD AHTAEVNCLS FNPYSEFILA TGSADKTVAL WDLRNLKLKL HSFESHKDEI FQVQWSPHNE TILASSGTDR RLNVWDLSKI GEEQSPEDAE DGPPELLFIH GGHTAKISDF SWNPNEPWVI CSVSEDNIMQ VWQMAENIYN DEDPEGSVDP EGQGS
    特异性
    Met1-Ser425
    纯度
    > 92 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 1.0 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Human RBBP4 Protein at 1 μg/mL (100 μL/well) can bind RBBP4 Rabbit pAb with a linear range of 0.976-7.09 ng/mL.
    Top Product
    Discover our top product RBBP4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of 50 mM Tris, 500 mM NaCl, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    Retinoblastoma Binding Protein 4 (RBBP4)
    别名
    RBBP-4 (RBBP4 产品)
    别名
    NURF55 Protein, RBAP48 Protein, 154659_at Protein, 55 Protein, CAF-1 Protein, CAF1 Protein, CAF1-55 Protein, CAF1p55 Protein, CG4236 Protein, Caf-1 Protein, Caf1/p55 Protein, Caf1p55 Protein, Dmel\\CG4236 Protein, MSI1/RbAp48/CAC3/LIN-53 Protein, NURF Protein, NURF-55 Protein, Nurf Protein, Nurf 55 Protein, Nurf-55 Protein, Nurf55 Protein, P55 Protein, RbAp48 Protein, S(ls)3 Protein, caf-1 Protein, caf1 Protein, caf1 p55 Protein, d-CAF1 Protein, dCAF-1 Protein, dCAF-1 p55 Protein, dNURF Protein, p55 Protein, p55 CAF1 Protein, p55/NURF-55 Protein, p55CAF1 Protein, nurf55 Protein, rbap48 Protein, xrbbp4 Protein, mRbAp48 Protein, RBBP4 Protein, rbb4-2 Protein, zgc:55349 Protein, zgc:77854 Protein, wu:fb33a09 Protein, wu:fb40e10 Protein, RBBP-4 Protein, rbbp4 Protein, M4E13.110 Protein, M4E13_110 Protein, MULTICOPY SUPPRESSOR OF IRA1 3 Protein, NFC3 Protein, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP C 3 Protein, RB binding protein 4, chromatin remodeling factor Protein, Chromatin assembly factor 1, p55 subunit Protein, retinoblastoma binding protein 4 Protein, retinoblastoma binding protein 4, chromatin remodeling factor Protein, retinoblastoma binding protein 4 L homeolog Protein, Transducin family protein / WD-40 repeat family protein Protein, retinoblastoma binding protein 4 S homeolog Protein, RBBP4 Protein, Caf1-55 Protein, rbbp4 Protein, Rbbp4 Protein, rbbp4.L Protein, MSI3 Protein, rbbp4.S Protein
    背景

    Description: Histone-binding protein RBBP4, also known as Retinoblastoma-binding protein 4, Retinoblastoma-binding protein p48, Chromatin assembly factor 1 subunit C, Chromatin assembly factor I p48 subunit, Nucleosome-remodeling factor subunit RBAP48 and RBBP4, is a nucleus protein which belongs to the WD repeat RBAP46/RBAP48/MSI1 family.It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes.

    Name: NURF55, RBAP48, lin-53,RBBP4,RBAP48,lin-53

    基因ID
    5928
    UniProt
    Q09028
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus
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