MUC1 Protein (Fc Tag,His tag)
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- 抗原 See all MUC1 蛋白
- MUC1 (Mucin 1 (MUC1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MUC1 protein is labelled with Fc Tag,His tag.
- 原理
- Active Recombinant Human MUC-1/CD227 Protein
- 序列
- MTPGTQSPFF LLLLLTVLTA TTAPKPATVV TGSGHASSTP GGEKETSATQ RSSVPSSTEK NAFNSSLEDP STDYYQELQR DISEMFLQIY KQGGFLGLSN IKFRPGSVVV QLTLAFREGT INVHDVETQF NQYKTEAASR YNLTISDVSV SDVPFPFSAQ SGAGVPG
- 特异性
- Met1-Gly167
- 纯度
- > 97 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its ability to increase beta-catenin levels in the cytoplasm and nucleus of HCT116 human colon adenocarcinoma cells. 0.01-1 ng/mL of Recombinant Human MUC-1 can effectively increase beta-catenin levels.
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- Discover our top product MUC1 蛋白
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Mucin 1 (MUC1) (AA 24-158) protein (Fc Tag)
MUC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mucin 1 (MUC1) (AA 315-420) protein (GST tag)MUC1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Mucin 1 (MUC1) (AA 24-380) (Active) protein (Fc Tag)MUC1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Mucin 1 (MUC1) (AA 1095-1140) protein (His tag)MUC1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Mucin 1 (MUC1) (AA 890-1158) protein (His tag)MUC1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Mucin 1 (MUC1) (AA 1036-1155) protein (His tag)MUC1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Mucin 1 (MUC1) (AA 1036-1156) protein (His tag)MUC1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- 抗原
- MUC1 (Mucin 1 (MUC1))
- 别名
- MUC-1/CD227 (MUC1 产品)
- 别名
- CA 15-3 Protein, CD227 Protein, EMA Protein, H23AG Protein, KL-6 Protein, MAM6 Protein, MCKD1 Protein, MUC-1 Protein, MUC-1/SEC Protein, MUC-1/X Protein, MUC1/ZD Protein, PEM Protein, PEMT Protein, PUM Protein, Muc-1 Protein, mucin 1, cell surface associated Protein, mucin 1, transmembrane Protein, MUC1 Protein, Muc1 Protein
- 背景
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Description: The protein is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
Name: ADMCKD,ADMCKD1,CA 15-3,CD227,EMA,H23AG,KL-6,MAM6,MCD,MCKD,MCKD1,MUC-1,MUC-1/SEC,MUC-1/X,MUC1/ZD,PEM,PEMT,PUM,MUC1,CA15-3,mucin-1, ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, CA15-3, mucin-1
- 基因ID
- 4582
- UniProt
- P15941-11
- 途径
- Negative Regulation of intrinsic apoptotic Signaling
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