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IL21 Receptor Protein (His tag)

IL21R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % by SDS-PAGE. Active
产品编号 ABIN7534805
发货至: 中国
  • 抗原 See all IL21 Receptor (IL21R) 蛋白
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 12
    • 4
    • 2
    • 1
    小鼠
    资源
    • 12
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL21 Receptor protein is labelled with His tag.
    原理
    Active Recombinant Mouse IL-21R/CD360 Protein
    序列
    CLDLTCYTDY LWTITCVLET RSPNPSILSL TWQDEYEELQ DQETFCSLHR SGHNTTHIWY TCHMRLSQFL SDEVFIVNVT DQSGNNSQEC GSFVLAESIK PAPPLNVTVA FSGRYDISWD SAYDEPSNYV LRGKLQYELQ YRNLRDPYAV RPVTKLISVD SRNVSLLPEE FHKDSSYQLQ VRAAPQPGTS FRGTWSEWSD PVIFQTQAGE PEAGWDP
    特异性
    Cys20-Pro236
    纯度
    > 97 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse IL21R at 2 μg/mL (100 μL/well) can bind Recombinant Human IL-21 with a linear range of 0.128-83.57 ng/mL.
    Top Product
    Discover our top product IL21R 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    别名
    IL-21R/CD360 (IL21R 产品)
    别名
    IL21R Protein, il-21ra.a Protein, CD360 Protein, NILR Protein, interleukin 21 receptor Protein, interleukin 21 receptor, tandem duplicate 1 Protein, IL21R Protein, il21r.1 Protein, Il21r Protein
    背景

    Description: Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R and NILR, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines,and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.

    Name: CD360,NILR,IL-21 R,IL-21 receptor,IL21R,IL-21R,interleukin 21 receptor,interleukin-21 receptor,IL21R

    基因ID
    60504
    UniProt
    Q9JHX3
    途径
    JAK/STAT Signaling
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