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IL17RA Protein (His tag)

IL17RA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
产品编号 ABIN7534426
发货至: 中国
  • 抗原 See all IL17RA 蛋白
    IL17RA (Interleukin 17 Receptor A (IL17RA))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 17
    • 6
    • 3
    资源
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL17RA protein is labelled with His tag.
    原理
    Active Recombinant Human IL-17RA/CD217 Protein
    序列
    LRLLDHRALV CSQPGLNCTV KNSTCLDDSW IHPRNLTPSS PKDLQIQLHF AHTQQGDLFP VAHIEWTLQT DASILYLEGA ELSVLQLNTN ERLCVRFEFL SKLRHHHRRW RFTFSHFVVD PDQEYEVTVH HLPKPIPDGD PNHQSKNFLV PDCEHARMKV TTPCMSSGSL WDPNITVETL EAHQLRVSFT LWNESTHYQI LLTSFPHMEN HSCFEHMHHI PAPRPEEFHQ RSNVTLTLRN LKGCCRHQVQ IQPFFSSCLN DCLRHSATVS CPEMPDTPEP IPDYMPLW
    特异性
    Leu33-Trp320
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    1.Measured by its ability to inhibit IL-17A induced IL-6 secretion by Hela cells. The ED50 for this effect is 0.02 0.1 μg/mL in the presence of 10 ng/mL recombinant human IL 17A.|2.Measured by its binding ability in a functional ELISA. Immobilized Recombinant human IL17RA , His Tag at 2 μg/mL (100 μL/well) can bind Recombinant human IL-17A,His Tag with a linear range of 31.25-65 ng/mL.
    Top Product
    Discover our top product IL17RA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    IL17RA (Interleukin 17 Receptor A (IL17RA))
    别名
    IL-17RA/CD217 (IL17RA 产品)
    别名
    IL17R Protein, CANDF5 Protein, CD217 Protein, CDw217 Protein, IL-17RA Protein, hIL-17R Protein, Il17r Protein, AW538159 Protein, Cdw217 Protein, VDw217 Protein, interleukin 17 receptor A Protein, IL17RA Protein, Il17ra Protein
    背景

    Description: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. This transmembrane protein (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.

    Name: CANDF5, CD217, CDw217, IL-17RA, IL17R, IMD51, hIL-17R,IL17RA,CD217,CDw217,IL-17RA,IL17R,IMD51,hIL-17R

    基因ID
    23765
    UniProt
    Q96F46
    途径
    SARS-CoV-2 Protein Interactome
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