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IDO1 蛋白

IDO1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % by SDS-PAGE.
产品编号 ABIN7533743
发货至: 中国
  • 抗原 See all IDO1 蛋白
    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 4
    • 1
    资源
    • 7
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    原理
    Active Recombinant Human IDO-1 Protein
    序列
    AHAMENSWTI SKEYHIDEEV GFALPNPQEN LPDFYNDWMF IAKHLPDLIE SGQLRERVEK LNMLSIDHLT DHKSQRLARL VLGCITMAYV WGKGHGDVRK VLPRNIAVPY CQLSKKLELP PILVYADCVL ANWKKKDPNK PLTYENMDVL FSFRDGDCSK GFFLVSLLVE IAAASAIKVI PTVFKAMQMQ ERDTLLKALL EIASCLEKAL QVFHQIHDHV NPKAFFSVLR IYLSGWKGNP QLSDGLVYEG FWEDPKEFAG GSAGQSSVFQ CFDVLLGIQQ TAGGGHAAQF LQDMRRYMPP AHRNFLCSLE SNPSVREFVL SKGDAGLREA YDACVKALVS LRSYHLQIVT KYILIPASQQ PKENKTSEDP SKLEAKGTGG TDLMNFLKTV RSTTEKSLLK EG
    特异性
    Ala2-Gly403
    纯度
    > 97 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product IDO1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of 50 mM Tris, 150 mM NaCl, pH 8.0.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
    别名
    IDO-1 (IDO1 产品)
    别名
    INDO Protein, ido Protein, indo Protein, IDO Protein, cd107b Protein, IDO1 Protein, IDO-1 Protein, Ido Protein, Indo Protein, indoleamine 2,3-dioxygenase 1 Protein, indoleamine 2,3-dioxygenase 1 L homeolog Protein, indoleamine 2,3-dioxygenase 1-like Protein, IDO1 Protein, ido1.L Protein, ido1 Protein, Ido1 Protein, LOC100050681 Protein
    背景

    Description: Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

    Name: IDO, IDO-1, INDO,IDO1,IDO-1,INDO,indoleamine 2

    基因ID
    3620
    UniProt
    P14902
    途径
    Activated T Cell Proliferation
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