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HTRA2 蛋白

HTRA2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 92 % by SDS-PAGE. Active
产品编号 ABIN7533786
发货至: 中国
  • 抗原 See all HTRA2 蛋白
    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    资源
    • 4
    • 2
    • 1
    大肠杆菌(E. Coli)
    原理
    Active Recombinant Human HTRA2 Protein
    序列
    AVPSPPPASP RSQYNFIADV VEKTAPAVVY IEILDRHPFL GREVPISNGS GFVVAADGLI VTNAHVVADR RRVRVRLLSG DTYEAVVTAV DPVADIATLR IQTKEPLPTL PLGRSADVRQ GEFVVAMGSP FALQNTITSG IVSSAQRPAR DLGLPQTNVE YIQTDAAIDF GNSGGPLVNL DGEVIGVNTM KVTAGISFAI PSDRLREFLH RGEKKNSSSG ISGSQRRYIG VMMLTLSPSI LAELQLREPS FPDVQHGVLI HKVILGSPAH RAGLRPGDVI LAIGEQMVQN AEDVYEAVRT QSQLAVQIRR GRETLTLYVT PEVTE
    特异性
    Ala134-Glu458
    纯度
    > 92 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    Biological Activity Comment
    Protease activity demonstrated by HtrA2 cleavage of bovine β-casein . Incubation of β-casein at 0.2 mg/mL with Recombinant Human HTRA-2 at 0.02 mg/mL (ratio of 10:1) for 60 minutes at 45°C in 50 mM Tris, pH 8.0, which results in >95% cleavage of β-casein, as revealed by SDS-PAGE.
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    Discover our top product HTRA2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
    别名
    HTRA2 (HTRA2 产品)
    别名
    CG8464 Protein, DmHtrA2 Protein, Dmel\\CG8464 Protein, HtrA2/Omi Protein, Omi Protein, dOmi Protein, domi Protein, htrA2 Protein, omi Protein, HTRA2 Protein, PRSS25 Protein, OMI Protein, PARK13 Protein, AI481710 Protein, Prss25 Protein, mnd2 Protein, HTRA2-related serine protease Protein, HtrA serine peptidase 2 Protein, HtrA2 Protein, HTRA2 Protein, htra2 Protein, Htra2 Protein
    背景

    Description: The protein is a serine protease. It has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed.

    Name: HTRA2,MGCA8,OMI,PARK13,PRSS25, OMI, PARK13, PRSS25

    基因ID
    27429
    UniProt
    O43464
    途径
    Positive Regulation of Endopeptidase Activity
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