HTRA2 蛋白
-
- 抗原 See all HTRA2 蛋白
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 原理
- Active Recombinant Human HTRA2 Protein
- 序列
- AVPSPPPASP RSQYNFIADV VEKTAPAVVY IEILDRHPFL GREVPISNGS GFVVAADGLI VTNAHVVADR RRVRVRLLSG DTYEAVVTAV DPVADIATLR IQTKEPLPTL PLGRSADVRQ GEFVVAMGSP FALQNTITSG IVSSAQRPAR DLGLPQTNVE YIQTDAAIDF GNSGGPLVNL DGEVIGVNTM KVTAGISFAI PSDRLREFLH RGEKKNSSSG ISGSQRRYIG VMMLTLSPSI LAELQLREPS FPDVQHGVLI HKVILGSPAH RAGLRPGDVI LAIGEQMVQN AEDVYEAVRT QSQLAVQIRR GRETLTLYVT PEVTE
- 特异性
- Ala134-Glu458
- 纯度
- > 92 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- Biological Activity Comment
- Protease activity demonstrated by HtrA2 cleavage of bovine β-casein . Incubation of β-casein at 0.2 mg/mL with Recombinant Human HTRA-2 at 0.02 mg/mL (ratio of 10:1) for 60 minutes at 45°C in 50 mM Tris, pH 8.0, which results in >95% cleavage of β-casein, as revealed by SDS-PAGE.
- Top Product
- Discover our top product HTRA2 蛋白
-
HtrA Serine Peptidase 2 (HTRA2) (full length) protein (His tag)
HTRA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
HtrA Serine Peptidase 2 (HTRA2) (AA 133-358) protein (His tag)HTRA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
HtrA Serine Peptidase 2 (HTRA2) (AA 359-458) protein (GST tag)HTRA2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
- 储存条件
- -20 °C,-80 °C
- 储存方法
-
Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
-
- 抗原
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- 别名
- HTRA2 (HTRA2 产品)
- 别名
- CG8464 Protein, DmHtrA2 Protein, Dmel\\CG8464 Protein, HtrA2/Omi Protein, Omi Protein, dOmi Protein, domi Protein, htrA2 Protein, omi Protein, HTRA2 Protein, PRSS25 Protein, OMI Protein, PARK13 Protein, AI481710 Protein, Prss25 Protein, mnd2 Protein, HTRA2-related serine protease Protein, HtrA serine peptidase 2 Protein, HtrA2 Protein, HTRA2 Protein, htra2 Protein, Htra2 Protein
- 背景
-
Description: The protein is a serine protease. It has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed.
Name: HTRA2,MGCA8,OMI,PARK13,PRSS25, OMI, PARK13, PRSS25
- 基因ID
- 27429
- UniProt
- O43464
- 途径
- Positive Regulation of Endopeptidase Activity
-
