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FKBP1A 蛋白

FKBP1A 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS-PAGE.
产品编号 ABIN7533808
发货至: 中国
  • 抗原 See all FKBP1A 蛋白
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    蛋白类型
    Recombinant
    宿主
    • 9
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    • 1
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    • 1
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    资源
    • 9
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    • 2
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human FKBP1A/FKBP12 Protein
    序列
    MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE
    特异性
    Met1-Glu108
    纯度
    > 90 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product FKBP1A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    别名
    FKBP1A/FKBP12 (FKBP1A 产品)
    背景

    Description: The protein is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor.

    Name: FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE,FKBP1A,FKBP-1A,FKBP1,FKBP12,PKC12,PKCI2,PPIASE

    基因ID
    2280
    UniProt
    P62942
    途径
    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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