EPH Receptor A3 Protein (EPHA3) (His tag)
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- 抗原 See all EPH Receptor A3 (EPHA3) 蛋白
- EPH Receptor A3 (EPHA3)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This EPH Receptor A3 protein is labelled with His tag.
- 原理
- Active Recombinant Human EphA3 Protein
- 序列
- MDCQLSILLL LSCSVLDSFG ELIPQPSNEV NLLDSKTIQG ELGWISYPSH GWEEISGVDE HYTPIRTYQV CNVMDHSQNN WLRTNWVPRN SAQKIYVELK FTLRDCNSIP LVLGTCKETF NLYYMESDDD HGVKFREHQF TKIDTIAADE SFTQMDLGDR ILKLNTEIRE VGPVNKKGFY LAFQDVGACV ALVSVRVYFK KCPFTVKNLA MFPDTVPMDS QSLVEVRGSC VNNSKEEDPP RMYCSTEGEW LVPIGKCSCN AGYEERGFMC QACRPGFYKA LDGNMKCAKC PPHSSTQEDG SMNCRCENNY FRADKDPPSM ACTRPPSSPR NVISNINETS VILDWSWPLD TGGRKDVTFN IICKKCGWNI KQCEPCSPNV RFLPRQFGLT NTTVTVTDLL AHTNYTFEID AVNGVSELSS PPRQFAAVSI TTNQAAPSPV LTIKKDRTSR NSISLSWQEP EHPNGIILDY EVKYYEKQEQ ETSYTILRAR GTNVTISSLK PDTIYVFQIR ARTAAGYGTN SRKFEFETSP DSFSISGESS Q
- 特异性
- Met1-Gln541
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 1.0 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Human EFNA5 at 0.5 μg/mL (100 μL/well) can bind Human EPHA3 with a linear range of 0.01-0.3 ng/mL.
- Top Product
- Discover our top product EPHA3 蛋白
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EPH Receptor A3 (EPHA3) (AA 1-514) protein (His tag)
EPHA3 宿主: 犬 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor A3 (EPHA3) (AA 21-541) protein (His tag)EPHA3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor A3 (EPHA3) (AA 21-541) protein (His tag)EPHA3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor A3 (EPHA3) (AA 21-541) protein (mFc-His Tag)EPHA3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
EPH Receptor A3 (EPHA3) (AA 202-326) protein (GST tag)EPHA3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor A3 (EPHA3) (AA 1-983) protein (GST tag)EPHA3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor A3 (EPHA3) (Active) protein (His tag)EPHA3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
EPH Receptor A3 (EPHA3) (AA 569-984) protein (GST tag,His tag)EPHA3 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
EPH Receptor A3 (EPHA3) (Active) protein (His tag)EPHA3 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
EPH Receptor A3 (EPHA3) (Active) protein (Fc Tag)EPHA3 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- 抗原
- EPH Receptor A3 (EPHA3)
- 别名
- EphA3 (EPHA3 产品)
- 别名
- EK4 Protein, ETK Protein, ETK1 Protein, HEK Protein, HEK4 Protein, TYRO4 Protein, EPHA3 Protein, AW492086 Protein, Cek4 Protein, End3 Protein, Hek Protein, Hek4 Protein, Mek4 Protein, Tyro4 Protein, CEK4 Protein, EPH receptor A3 Protein, ephrin type-A receptor 3 Protein, Eph receptor A3 Protein, EPHA3 Protein, LOC100439679 Protein, Epha3 Protein
- 背景
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Description: EphA3, also known as Cek4, Mek4, Hek, Tyro4, and Hek4, is a 135 kDa glycosylated member of the transmembrane Eph receptor tyrosine kinase family. EphA3 is expressed in the developing forebrain, retinal axons, some spinal cord motor neurons, and the heart where it plays an important role in axonal repulsion and organ morphogenesis. It is upregulated on some hematopoietic and solid tumor cells and on astrocytes surrounding injured nervous tissue . EphA3 ligation inhibits cellular adhesion to fibronectin as well as cellular migration. Transmembrane EphA3 associates in cis with ADAM10 which then promotes the cleavage in trans of Ephrin-A5. It also associates in cis with Ephrin-A5 on retinal axons, thereby preventing the activation of EphA3 by Ephrin-A.
Name: EK4,ETK,HEK,ETK1,HEK4,TYRO4,EPHA3
- 基因ID
- 2042
- UniProt
- P29320
- 途径
- RTK signaling, Regulation of Cell Size
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