CSH1 Protein (His tag)
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- 抗原 See all CSH1 蛋白
- CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CSH1 protein is labelled with His tag.
- 原理
- Recombinant Human Chorionic somatomammotropin hormone 1/Choriomammotropin/CSH1 Protein
- 序列
- VQTVPLSRLF DHAMLQAHRA HQLAIDTYQE FEETYIPKDQ KYSFLHDSQT SFCFSDSIPT PSNMEETQQK SNLELLRISL LLIESWLEPV RFLRSMFANN LVYDTSDSDD YHLLKDLEEG IQTLMGRLED GSRRTGQILK QTYSKFDTNS HNHDALLKNY GLLYCFRKDM DKVETFLRMV QCRSVEGSCG F
- 特异性
- Val27-Phe217
- 纯度
- > 97 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- <0.001EU/μg
- Top Product
- Discover our top product CSH1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 浓度
- 0.7 mg/mL
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))
- 别名
- Chorionic somatomammotropin hormone 1/Choriomammotropin/CSH1 (CSH1 产品)
- 别名
- CS-1 Protein, CSA Protein, CSMT Protein, PL Protein, hCS-A Protein, CS-2 Protein, CSB Protein, hCS-B Protein, chorionic somatomammotropin hormone 1 Protein, chorionic somatomammotropin hormone 2 Protein, CSH1 Protein, CSH2 Protein
- 背景
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Description: Chorionic somatomammotropin hormone, also known as Choriomammotropin, Lactogen, Placental lactogen and CSH1, is a secreted protein which belongs to thesomatotropin / prolactin family. CSH1 is produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. The CSH1 gene is member of the GH gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. Genomic alterations in the GH cluster are well known, causing different phenotypes depending on the size of the deletion and the genes involved. The increased prevalence of hemizygosity of CSH1 in population in comparison to controls indicates a role for CSH1 haploinsufficiency in the etiology of growth retardation. Investigation of CSH1 deletions in further SRS and growth retarded patients will enable us to establish under which circumstances haploinsufficiency of CSH1 is likely to result in clinical changes.
Name: PL, CSA, CS-1, CSMT, GHB3, hCS-1, hCS-A
- 基因ID
- 1442
- UniProt
- P0DML2
- 途径
- Response to Growth Hormone Stimulus
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