CCL13 蛋白
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- 抗原 See all CCL13 蛋白
- CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Yeast (Pichia pastoris)
- 原理
- Recombinant Human CCL13/MCP-4 Protein
- 序列
- QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT
- 特异性
- Gln24-Thr98
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- <0.1EU/μg
- Top Product
- Discover our top product CCL13 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))
- 别名
- CCL13/MCP-4 (CCL13 产品)
- 别名
- CKb10 Protein, MCP-4 Protein, NCC-1 Protein, NCC1 Protein, SCYA13 Protein, SCYL1 Protein, C-C motif chemokine ligand 13 Protein, chemokine (C-C motif) ligand 13 Protein, CCL13 Protein
- 背景
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Description: Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chemokines, CCL13 binds to several chemokine receptors (CCR1, CCR2 and CCR3), allowing it to elicit different effects on its target cells. A number of studies have shown that CCL13 is involved in many chronic inflammatory diseases, in which it functions as a pivotal molecule involved in the selective recruitment of cell lineages to the inflamed tissues and their subsequent activation. MCP-4/CCL13 is secreted from chondrocytes and activates the proliferation of rheumatoid synovial cells, thereby leading to joint destruction in RA.
Name: CCL13,CKb10,MCP-4,NCC-1,NCC1,SCYA13,SCYL1
- 基因ID
- 6357
- UniProt
- Q99616
- 途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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