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CD2 Protein (CD2) (His tag)

CD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
产品编号 ABIN7534345
发货至: 中国
  • 抗原 See all CD2 蛋白
    CD2
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 16
    • 3
    • 1
    • 1
    • 1
    资源
    • 11
    • 4
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD2 protein is labelled with His tag.
    原理
    Active Recombinant Human CD2 Protein
    序列
    KEITNALETW GALGQDINLD IPSFQMSDDI DDIKWEKTSD KKKIAQFRKE KETFKEKDTY KLFKNGTLKI KHLKTDDQDI YKVSIYDTKG KNVLEKIFDL KIQERVSKPK ISWTCINTTL TCEVMNGTDP ELNLYQDGKH LKLSQRVITH KWTTSLSAKF KCTAGNKVSK ESSVEPVSCP EKGLD
    特异性
    Lys25-Asp209
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA.Immobilized Human CD2 at 2 μg/mL (100 μL/well) can bind Human CD58 with a linear range of 1.22-34.4 ng/mL.
    Top Product
    Discover our top product CD2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    CD2
    别名
    CD2 (CD2 产品)
    别名
    CD2 Protein, LFA-2 Protein, Ly-37 Protein, Ly37 Protein, SRBC Protein, T11 Protein, CD2R Protein, LFA2 Protein, OX-34 Protein, OX34 Protein, CD2 molecule Protein, CD2 antigen Protein, Cd2 molecule Protein, CD2 Protein, Cd2 Protein
    背景

    Description: T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, and SRBC, is a single-pass type I membrane protein. It contains one Ig-like C2-type domain and one Ig-like V-type domain. CD2 is a cell adhesion molecule expressed on T cells and is recognized as a target for CD48 (rats) and CD58 (humans). Further, intracellular CD2 signaling pathways and networks are being discovered by the identification of several cytosolic tail binding proteins. CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain of CD2 is implicated in the signaling function. The complex of CD2 and CD58 also plays an important role in enhancing the adhesion of T lymphocytes to target cells, and promoting hyperplasia and activation of T lymphocytes. As a cell surface glycoprotein, CD2 expressed on most human T cells and natural killer (NK) cells and plays an important role in mediating cell adhesion in both T-lymphocytes and in signal transduction.

    Name: CD2,LFA-2,SRBC,T11

    基因ID
    914
    UniProt
    P06729
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