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Betacellulin Protein (BTC) (Fc Tag)

BTC 宿主: 人 宿主: HEK-293 Cells Recombinant > 92 % by SDS-PAGE.
产品编号 ABIN7536289
发货至: 中国
  • 抗原 See all Betacellulin (BTC) 蛋白
    Betacellulin (BTC)
    蛋白类型
    Recombinant
    宿主
    • 13
    • 5
    • 4
    • 2
    • 2
    资源
    • 15
    • 4
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    • 2
    • 1
    HEK-293 Cells
    标记
    This Betacellulin protein is labelled with Fc Tag.
    原理
    Recombinant Human Betacellulin/BTC Protein
    序列
    DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
    特异性
    Asp32-Tyr111
    纯度
    > 92 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    <0.1EU/μg
    Top Product
    Discover our top product BTC 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    浓度
    0.8 mg/mL
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    Betacellulin (BTC)
    别名
    Betacellulin/BTC (BTC 产品)
    别名
    BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
    背景

    Description: Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth factor receptor (EGFR), neu/ErbB-2/HER2, ErbB-3/HER3 and ErbB-4/HER4). Betacellulin is a 32-kilodalton glycoprotein that appears to be processed from a larger transmembrane precursor by proteolytic cleavage. This protein is a ligand for the EGF receptor. BTC is a polymer of about 62-111 amino acid residues. Secondary Structure: 6 % helical (1 helices, 3 residues)36 % beta sheet (5 strands, 18 residues). BTC was originally identified as a growth-promoting factor in mouse pancreatic β-cell carcinoma cell line and has since been identified in humans. It plays a role in the growth and development of the neonate and/or mammary gland function. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.

    Name: BTC,Betacellulin

    基因ID
    685
    UniProt
    P35070
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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