Growth Hormone Receptor Protein (GHR) (AA 1-265) (His tag)
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- 抗原 See all Growth Hormone Receptor (GHR) 蛋白
- Growth Hormone Receptor (GHR)
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-265
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This Growth Hormone Receptor protein is labelled with His tag.
- 序列
- Met 1-Arg 265
- 产品特性
- A DNA sequence encoding the Rat GHR protein (P16310) (Met 1-Arg 265) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
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- Discover our top product GHR 蛋白
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Growth Hormone Receptor (GHR) (AA 27-264) protein (His tag)
GHR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Hormone Receptor (GHR) (AA 27-264) (Active) protein (His tag)GHR 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Growth Hormone Receptor (GHR) protein (Fc Tag)GHR 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Growth Hormone Receptor (GHR) (AA 19-118) protein (GST tag)GHR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Hormone Receptor (GHR) (AA 27-264) protein (Fc Tag)GHR 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Growth Hormone Receptor (GHR) (Active) protein (His tag,Fc Tag)GHR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Growth Hormone Receptor (GHR) (Active) protein (His tag)GHR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Growth Hormone Receptor (GHR) (Active) protein (Fc Tag)GHR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Growth Hormone Receptor (GHR) (Active) protein (His tag)GHR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Growth Hormone Receptor (GHR) (AA 27-264) (Active) protein (Fc Tag)GHR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Growth Hormone Receptor (GHR)
- 别名
- Growth Hormone Receptor (GHR 产品)
- 别名
- GHBP Protein, AA986417 Protein, GHR/BP Protein, GHR Protein, ghr Protein, ghr.a Protein, zgc:162141 Protein, growth hormone receptor Protein, growth hormone receptor L homeolog Protein, growth hormone receptor a Protein, GHR Protein, Ghr Protein, ghr.L Protein, ghr Protein, ghra Protein
- 背景
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Abbreviation: Growth Hormone Receptor,GHR
Target Synonym: GHR/BP,MGC124963,MGC156665
Background: Growth hormone receptor, also known as GH receptor and GHR, is a single-pass type I membrane protein which belongs to thetype I cytokine receptor family and type 1 subfamily. GHR contains onefibronectin type-III domain. Growth hormone receptor / GHR is expressed in various tissues with high expression in liver and skeletal muscle. Isoform4of GHR is predominantly expressed in kidney, bladder, adrenal gland and brain stem. Isoform1 expression of GHR in placenta is predominant in chorion and decidua. Isoform4is highly expressed in placental villi. Isoform2of GHR is expressed in lung, stomach and muscle. Growth hormone receptor / GHR is a receptor for pituitary gland growth hormone. It is involved in regulating postnatal body growth. On ligand binding, it couples to the JAK2 / STAT5 pathway. Isoform2of GHR up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling. Defects in GHR are a cause of Laron syndrome (LARS) which is a severe form of growth hormone insensitivity characterized by growth impairment, short stature, dysfunctional growth hormone receptor, and failure to generate insulin-like growth factor I in response to growth hormone. Defects in GHR may also be a cause of idiopathic short stature autosomal (ISSA) which is defined by a subnormal rate of growth.
- 分子量
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Calculated MW: 29.04 kDa
Observed MW: 36 kDa
- UniProt
- P16310
- 途径
- NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
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