CA9 Protein (AA 1-390) (His tag)
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- 抗原 See all CA9 蛋白
- CA9 (Carbonic Anhydrase IX (CA9))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-390
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This CA9 protein is labelled with His tag.
- 序列
- Met1-Asp390
- 产品特性
- A DNA sequence encoding the Mouse CA9 protein (Q8VHB5) (Met1-Asp390) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CA9 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- CA9 (Carbonic Anhydrase IX (CA9))
- 别名
- Carbonic Anhydrase 9 (CA9 产品)
- 别名
- CA9 Protein, CAIX Protein, Ca9 Protein, MN/CA9 Protein, MN Protein, carbonic anhydrase 9 Protein, CA9 Protein, CAH9 Protein, Car9 Protein
- 背景
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Abbreviation: Carbonic Anhydrase 9;CA9
Target Synonym: RP23-195K8.9;CAIX;Ca9;MN/CA9
Background: Carbonic anhydrases 9 (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. Cas are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.
- 分子量
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Calculated MW: 42.79 kDa
Observed MW: 50 kDa
- UniProt
- Q8VHB5
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