PLAU Protein (AA 1-431) (His tag)
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- 抗原 See all PLAU 蛋白
- PLAU (Plasminogen Activator, Urokinase (PLAU))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-431
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PLAU protein is labelled with His tag.
- 序列
- Met1-Leu431
- 产品特性
- A DNA sequence encoding the Human PLAU protein (P00749) (Met1-Leu431) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PLAU 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- PLAU (Plasminogen Activator, Urokinase (PLAU))
- 别名
- Urokinase (PLAU 产品)
- 别名
- PLAU Protein, u-PA Protein, ATF Protein, BDPLT5 Protein, QPD Protein, UPA Protein, URK Protein, uPA Protein, UPAM Protein, plasminogen activator, urokinase Protein, urokinase-type plasminogen activator Protein, PLAU Protein, CpipJ_CPIJ002131 Protein, CpipJ_CPIJ006543 Protein, CpipJ_CPIJ013396 Protein, CpipJ_CPIJ013623 Protein, Plau Protein
- 背景
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Abbreviation: Urokinase,uPA
Target Synonym: Urokinase-Type Plasminogen Activator,U-Plasminogen Activator,uPA,PLAU,ATF,BDPLT5,QPD,u-PA,UPA,URK
Background: Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.
- 分子量
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Calculated MW: 47.3 kDa
Observed MW: 45 kDa
- UniProt
- P00749
- 途径
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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