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PLAU Protein (AA 1-431) (His tag)

PLAU 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505721
发货至: 中国
  • 抗原 See all PLAU 蛋白
    PLAU (Plasminogen Activator, Urokinase (PLAU))
    蛋白类型
    Recombinant
    产品特性
    AA 1-431
    宿主
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    资源
    • 14
    • 10
    • 6
    • 1
    HEK-293 Cells
    标记
    This PLAU protein is labelled with His tag.
    序列
    Met1-Leu431
    产品特性
    A DNA sequence encoding the Human PLAU protein (P00749) (Met1-Leu431) was expressed with a C-His.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product PLAU 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    PLAU (Plasminogen Activator, Urokinase (PLAU))
    别名
    Urokinase (PLAU 产品)
    别名
    PLAU Protein, u-PA Protein, ATF Protein, BDPLT5 Protein, QPD Protein, UPA Protein, URK Protein, uPA Protein, UPAM Protein, plasminogen activator, urokinase Protein, urokinase-type plasminogen activator Protein, PLAU Protein, CpipJ_CPIJ002131 Protein, CpipJ_CPIJ006543 Protein, CpipJ_CPIJ013396 Protein, CpipJ_CPIJ013623 Protein, Plau Protein
    背景

    Abbreviation: Urokinase,uPA

    Target Synonym: Urokinase-Type Plasminogen Activator,U-Plasminogen Activator,uPA,PLAU,ATF,BDPLT5,QPD,u-PA,UPA,URK

    Background: Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.

    分子量

    Calculated MW: 47.3 kDa

    Observed MW: 45 kDa

    UniProt
    P00749
    途径
    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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