LILRB5 Protein (AA 1-458) (His tag)
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- 抗原 See all LILRB5 蛋白
- LILRB5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 5 (LILRB5))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-458
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LILRB5 protein is labelled with His tag.
- 序列
- Met1-Gly458
- 产品特性
- A DNA sequence encoding the Human LILRB5/CD85c protein (O75023) (Met1-Gly458) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product LILRB5 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- LILRB5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 5 (LILRB5))
- 别名
- LILRB5 (LILRB5 产品)
- 别名
- LILRB5 Protein, CD85C Protein, LIR-8 Protein, LIR8 Protein, leukocyte immunoglobulin-like receptor subfamily B member 5 Protein, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 Protein, leukocyte immunoglobulin like receptor B5 Protein, LOC695256 Protein, LILRB5 Protein
- 背景
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Abbreviation: LILRB5,CD85c
Target Synonym: Leukocyte immunoglobulin-like receptor subfamily B member 5,CD85 antigen-like family member C,Leukocyte immunoglobulin-like receptor 8,LIR-8,CD85c,LILRB5,LIR8
Background: Human Leukocyte Immunoglobulin-like Receptor Subfamily B Member 5 (LILRB5/CD85c/LIR-8) belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Iglike domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). Alternative splicing of human LIR-8 generates an isoform that lacks the second Ig-like domain. LIR-8 is expressed on NK cells and in the tryptic granules of mast cells. Following cell activation and degranulation, it is present on the mast cell surface. Activated mast cells may also release soluble forms of LIR-8.
- 分子量
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Calculated MW: 50.27 kDa
Observed MW: 70 kDa
- UniProt
- O75023
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