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NCR3 Protein (AA 1-135) (His tag)

NCR3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505697
发货至: 中国
  • 抗原 See all NCR3 蛋白
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    蛋白类型
    Recombinant
    产品特性
    AA 1-135
    宿主
    • 18
    • 2
    • 1
    • 1
    • 1
    资源
    • 9
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This NCR3 protein is labelled with His tag.
    序列
    Met1-Gly135
    产品特性
    A DNA sequence encoding the Human NKp30/NCR3 protein (O14931) (Met1-Gly135) was expressed with a C-His.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product NCR3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    别名
    NKp30 (NCR3 产品)
    别名
    MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
    背景

    Abbreviation: NKp30,NCR3

    Target Synonym: Natural Cytotoxicity Triggering Receptor 3,Activating Natural Killer Receptor p30,Natural Killer Cell p30-Related Protein,NK-p30,NKp30,CD337,NCR3,1C7,LY117,1C7,DAAP-90L16.3,MALS

    Background: Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive, but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity, and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.

    分子量

    Calculated MW: 14.74 kDa

    Observed MW: 25 kDa

    UniProt
    O14931
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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