TIMP1 Protein (AA 1-207) (His tag)
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- 抗原 See all TIMP1 蛋白
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-207
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TIMP1 protein is labelled with His tag.
- 序列
- Met1-Ala207
- 产品特性
- A DNA sequence encoding the Human TIMP-1 protein (P01033) (1-207) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product TIMP1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- 别名
- TIMP-1 (TIMP1 产品)
- 别名
- TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein
- 背景
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Abbreviation: TIMP-1
Target Synonym: Metalloproteinase Inhibitor 1,Erythroid-Potentiating Activity,EPA,Fibroblast collagenase Inhibitor,Collagenase Inhibitor,Tissue Inhibitor of Metalloproteinases 1,TIMP-1,TIMP1,CLGI,TIMP,CLGI,EPA,EPO,HCI
Background: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. Timp-1 complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It also mediates erythropoiesis in vitro, but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16, without MMP-14.
- 分子量
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Calculated MW: 22.66 kDa
Observed MW: 30 kDa
- UniProt
- P01033
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