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TIMP1 Protein (AA 1-207) (His tag)

TIMP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505680
发货至: 中国
  • 抗原 See all TIMP1 蛋白
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-207
    宿主
    • 9
    • 7
    • 3
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    • 3
    • 3
    • 3
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    • 1
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    资源
    • 15
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    • 3
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    • 1
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    HEK-293 Cells
    标记
    This TIMP1 protein is labelled with His tag.
    序列
    Met1-Ala207
    产品特性
    A DNA sequence encoding the Human TIMP-1 protein (P01033) (1-207) was expressed with a C-His.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product TIMP1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    别名
    TIMP-1 (TIMP1 产品)
    别名
    TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein
    背景

    Abbreviation: TIMP-1

    Target Synonym: Metalloproteinase Inhibitor 1,Erythroid-Potentiating Activity,EPA,Fibroblast collagenase Inhibitor,Collagenase Inhibitor,Tissue Inhibitor of Metalloproteinases 1,TIMP-1,TIMP1,CLGI,TIMP,CLGI,EPA,EPO,HCI

    Background: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. Timp-1 complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It also mediates erythropoiesis in vitro, but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16, without MMP-14.

    分子量

    Calculated MW: 22.66 kDa

    Observed MW: 30 kDa

    UniProt
    P01033
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