MMP8 Protein (AA 1-467) (His tag)
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- 抗原 See all MMP8 蛋白
- MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-467
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MMP8 protein is labelled with His tag.
- 序列
- Met1-Gly467
- 产品特性
- A DNA sequence encoding the Human MMP8 protein (P22894) (Met1-Gly467) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MMP8 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
- 别名
- MMP8 (MMP8 产品)
- 别名
- MMP8 Protein, BB138268 Protein, CLG1 Protein, HNC Protein, MMP-8 Protein, PMNL-CL Protein, matrix metallopeptidase 8 Protein, neutrophil collagenase Protein, MMP8 Protein, Mmp8 Protein, LOC100339790 Protein
- 背景
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Abbreviation: MMP8,CLG1
Target Synonym: Neutrophil collagenase,Matrix metalloproteinase-8,MMP-8,PMNL collagenase,PMNL-CL,MMP8,CLG1
Background: Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a member of the peptidase M10A family. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumour may have a protective effect against lymph node metastasis. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 participates in wound repair by contributing to the resolution of inflammation and open the possibility to develop new strategies for treating wound healing defects.
- 分子量
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Calculated MW: 51.26 kDa
Observed MW: 75 kDa
- UniProt
- P22894
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