Fibronectin Protein (AA 607-1265) (His tag)
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- 抗原 See all Fibronectin 蛋白
- Fibronectin
- 蛋白类型
- Recombinant
- 产品特性
- AA 607-1265
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Fibronectin protein is labelled with His tag.
- 序列
- Ser607-Pro1265
- 产品特性
- A DNA sequence encoding the Human FN protein (P02751) (Ser607-Pro1265) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product Fibronectin 蛋白
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Fibronectin (AA 1087-1172) protein (His tag)
宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibronectin (AA 1008-1231) protein (His-IF2DI Tag)宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Fibronectin
- Abstract
- Fibronectin 产品
- 别名
- FN Protein, cig Protein, fibronectin Protein, finc Protein, lets Protein, msf Protein, CIG Protein, ED-B Protein, FINC Protein, FNZ Protein, GFND Protein, GFND2 Protein, LETS Protein, MSF Protein, E330027I09 Protein, Fn Protein, Fn-1 Protein, FIBNEC Protein, fn-1 Protein, fibronectin 1 Protein, FN1 Protein, fn1 Protein, Fn1 Protein
- 背景
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Abbreviation: Fibronectin,FN
Target Synonym: Fibronectin,FN1,CIG,ED-B,FINC,FN,FNZ,GFND,GFND2,LETS,MSF
Background: Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet thrombus formation and diseases associated with thrombosis including vascular remodeling, atherosclerosis, and cardiac repair following a myocardial infarct. Each monomer of FN consists of three types of homologous repeating units, that is 12 type I repeats, two type II repeats and 15-17 type III repeats. The occurrence of multiple isoforms results from alternative mRNA splicing of the ED-A, ED-B and III-CS regions, and subsequent post-translational modification. As an ECM component and one of the primary cell adhesion molecules, Fibronectin can be a ligand for fibrin, heparin, chondroitin sulfate, collagen/gelatin, as well as many integrin receptors through which FN mediates the variety of cellular signaling pathways. The study of solid human tumors showed among the early signs of malignant transformation the fragmentation of pericellular FN, concommitent with the increase of its production by the peritumoral stroma. These results should encourage further investigations concerning the potential importance of Fn production and breakdown during cancer progression. FN1 expression has been described to increase significantly from the morula towards the early blastocyst stage, suggesting that FN1 may also be involved in early blastocyst formation.
- 分子量
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Calculated MW: 72.38 kDa
Observed MW: 80 kDa
- UniProt
- P02751
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