DNASE1 Protein (AA 1-282) (His tag)
-
- 抗原 See all DNASE1 蛋白
- DNASE1 (Deoxyribonuclease I (DNASE1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-282
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This DNASE1 protein is labelled with His tag.
- 序列
- Met 1-Lys282
- 产品特性
- A DNA sequence encoding the Human DNASE1 protein (P24855) (Met 1-Lys282) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product DNASE1 蛋白
-
Deoxyribonuclease I (DNASE1) (AA 23-282) protein (His-IF2DI Tag)
DNASE1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Deoxyribonuclease I (DNASE1) (AA 1-282) protein (GST tag)DNASE1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Deoxyribonuclease I (DNASE1) protein (GST tag,His tag)DNASE1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Deoxyribonuclease I (DNASE1) (AA 19-259) (Active) protein (His tag)DNASE1 宿主: 人 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
-
- 抗原
- DNASE1 (Deoxyribonuclease I (DNASE1))
- 别名
- Deoxyribonuclease 1 (DNASE1 产品)
- 别名
- LOC397802 Protein, DNL1 Protein, DRNI Protein, AI788650 Protein, DNaseI Protein, Dnl1 Protein, dnase1-A Protein, zgc:92440 Protein, DNase I Protein, deoxyribonuclease 1 Protein, deoxyribonuclease I Protein, deoxyribonuclease I L homeolog Protein, Deoxyribonuclease I Protein, endA Protein, LOC397802 Protein, DNASE1 Protein, Dnase1 Protein, dnase1.L Protein, dnase1 Protein, CpipJ_CPIJ011184 Protein, CpipJ_CPIJ011185 Protein, CpipJ_CPIJ011186 Protein, CpipJ_CPIJ011187 Protein, CpipJ_CPIJ011190 Protein, CpipJ_CPIJ017803 Protein, Desal_1409 Protein, MPET_RS05255 Protein, METEV_RS02275 Protein, Plabr_0631 Protein
- 背景
-
Abbreviation: Deoxyribonuclease 1,DNASE1
Target Synonym: Deoxyribonuclease-1,EC 3.1.21.1,Deoxyribonuclease I,DNase I,Dornase alfa,DNASE1,DNL1,DRNI
Background: DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. DNaseI binds to the cytoskeletal protein actin. It binds actin monomers with very high (sub-nanomolar) affinity and actin polymers with lower affinity. Mutations in DNase1 gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. DNase1 is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity.
- 分子量
-
Calculated MW: 30.91 kDa
Observed MW: 40 kDa
- UniProt
- P24855
-
