Renin Protein (REN) (AA 1-406) (His tag)
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- 抗原 See all Renin (REN) 蛋白
- Renin (REN)
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-406
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Renin protein is labelled with His tag.
- 序列
- Met1-Arg406
- 产品特性
- A DNA sequence encoding the Human REN protein (P00797) (Met1-Arg406) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product REN 蛋白
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Renin (REN) protein (His tag)
REN 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Renin (REN) (AA 24-406) protein (GST tag)REN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Renin (REN) (Active) protein (His tag)REN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Renin (REN)
- 别名
- Renin (REN 产品)
- 别名
- HNFJ2 Protein, RATRENAA Protein, RENAA Protein, Ren1 Protein, D19352 Protein, Ren Protein, Ren-1 Protein, Ren-A Protein, Ren1c Protein, Ren1d Protein, Rn-1 Protein, Rnr Protein, renin Protein, renin 1 structural Protein, REN Protein, Ren Protein, Ren1 Protein, ren Protein
- 背景
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Abbreviation: Renin,REN
Target Synonym: Renin,Angiotensinogenase,REN,Angiotensin-forming enzyme
Background: Renin is a member of the aspartyl proteinase family produced largely in part by the juxtaglomerular cells in the kidney. Renin is produced as prorenin with 43 pro residues at the N-terminal of mature Renin. The inactive prorenin becomes activated proteolytically by trypsin, cathepsin B, or other proteinases. Renin also has a very high selectivity for substrates due to a long peptide recognition on either side of the peptide bond undergoing cleavage. An octapeptide substrate was the minimum length to be cleaved by Renin. Renin plays a crucial role in the regulation of blood pressure and salt balance through the cleavage of angiotensinogen,which is the only known physiological substrate of Renin. Renin releases the decapeptide angiotensin I, which in turn is further converted to vasoactive hormone angiotensin II by angiotensin converting enzyme (ACE).
- 分子量
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Calculated MW: 44.55 kDa
Observed MW: 50 kDa
- UniProt
- P00797
- 途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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