IGFBP7 Protein (AA 1-282) (His tag)
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- 抗原 See all IGFBP7 蛋白
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-282
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IGFBP7 protein is labelled with His tag.
- 序列
- Met1-Leu282
- 产品特性
- A DNA sequence encoding the Human IGFBP-7 protein (Q16270) (Met1-Leu282) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IGFBP7 蛋白
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Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 26-281) protein (His tag)
IGFBP7 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 27-282) protein (His tag)IGFBP7 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
- 别名
- IGFBP-7 (IGFBP7 产品)
- 别名
- zgc:85888 Protein, AGM Protein, FSTL2 Protein, IBP-7 Protein, IGFBP-7 Protein, IGFBP-7v Protein, IGFBPRP1 Protein, MAC25 Protein, PSF Protein, RAMSVPS Protein, TAF Protein, Fstl2 Protein, Mac25 Protein, insulin like growth factor binding protein 7 Protein, insulin-like growth factor binding protein 7 Protein, IGFBP7 Protein, igfbp7 Protein, Igfbp7 Protein
- 背景
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Abbreviation: IGFBP-7
Target Synonym: Insulin-like growth factor-binding protein 7,IGFBP7,IGF-binding protein 7,IGFBP-rP1,MAC25 protein,Tumor-derived adhesion factor,TAF
Background: Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase inhibitor domain and a C-terminal immunoglobulin-like C2-type domain. Human and mouse IGFBP7 are highly homologous and share 94 % aa sequence identity. It is expressed in many normal tissues and in cancer cells. It is abundantly expressed in high endothelial venules (HEVs) of blood vessels in the secondary lymphoid tissues. It binds IGF and insulin with very low affinity and has been shown to enhance the mitogenic actions of IGF and insulin. IGFBP7 also has IGF/insulin-independent activities. It interacts with heparan sulfate proteoglycans, type IV collagen, and specific chemokines. It supports weak cell adhesion, promotes cell spreading on type IV collagen, and stimulates the production of the potent vasodilator PGI2. It modulates tumor cell growth and has also been implicated in angiogenesis.
- 分子量
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Calculated MW: 30.91 kDa
Observed MW: 32 kDa
- UniProt
- Q16270
- 途径
- Growth Factor Binding
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