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IGHG4 Protein (AA 99-327) (His tag,Fc Tag)

IGHG4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505663
发货至: 中国
  • 抗原 See all IGHG4 products
    IGHG4 (Immunoglobulin Heavy Constant gamma 4 (G4m Marker) (IGHG4))
    蛋白类型
    Recombinant
    产品特性
    AA 99-327
    宿主
    资源
    • 2
    • 1
    HEK-293 Cells
    标记
    This IGHG4 protein is labelled with His tag,Fc Tag.
    序列
    Glu99-Lys327
    产品特性
    A DNA sequence encoding the Human IgG4 protein (P01861) (Glu99-Lys327) was expressed with a C-His.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    IGHG4 (Immunoglobulin Heavy Constant gamma 4 (G4m Marker) (IGHG4))
    别名
    IGHG4 (IGHG4 产品)
    别名
    immunoglobulin heavy constant gamma 4 (G4m marker) Protein, IGHG4 Protein
    背景

    Abbreviation: IgG4-Fc

    Target Synonym: Ig gamma-4 chain C region,IgG4 Fc,IGHG4

    Background: SCN3B (sodium channel, voltage-gated, type III, beta ,human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. Defects in SCN3B are the cause of Brugada syndrome type 7. A tachyarrhythmia characterized by right bundle branch block and ST segment elevation on an electrocardiogram. It can cause the ventricles to beat so fast that the blood is prevented from circulating efficiently in the body. When this situation occurs (called ventricular fibrillation), the individual will faint and may die in a few minutes if the heart is not reset.

    分子量

    Calculated MW: 25.08 kDa

    Observed MW: 35 kDa

    UniProt
    P01861
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