FBLN2 Protein (AA 1-1184) (His tag)
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- 抗原 See all FBLN2 蛋白
- FBLN2 (Fibulin 2 (FBLN2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-1184
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FBLN2 protein is labelled with His tag.
- 序列
- Met1-Leu1184
- 产品特性
- A DNA sequence encoding the Human FBLN2 protein (P98095) (Met1-Leu1184) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FBLN2 蛋白
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Fibulin 2 (FBLN2) (AA 1076-1184) protein (GST tag)
FBLN2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibulin 2 (FBLN2) (AA 28-1184) protein (GST tag)FBLN2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibulin 2 (FBLN2) proteinFBLN2 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- FBLN2 (Fibulin 2 (FBLN2))
- 别名
- FBLN2 (FBLN2 产品)
- 别名
- 5730577E14Rik Protein, fibulin 2 Protein, fibulin-2 Protein, FBLN2 Protein, fbln2 Protein, LOC100440421 Protein, Fbln2 Protein
- 背景
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Abbreviation: FBLN2
Target Synonym: Fibulin-2 (FIBL-2),FBLN2
Background: Fibulin 2 is the second largest member of the seven-member fibulin family of extracellular membrane (ECM) glycoproteins. Fibulin-2 consists of 1184 amino acids (aa) with a predicted molecular weight of ~125 kDa. The overall structure is common to fibulins: 3 Anaphylatoxin (AT)-like domains, 11 Epidermal Growth Factor (EGF)?like domains, and a Fibulin-type carboxy-terminal (FC) domain. Fibulin 2 is considered a Class I fibulin because the 400-residue N-terminus is divided into the Na and Nb sections, with the Na section containing 150-residues and 12 cysteines while the remaining Nb section is cysteine-free. The protein is known to form disulfide-linked homodimers, but it can also be secreted as an oligomer. Fibulin 2 is highly conserved across species, with the human protein sharing 82 % amino acid identity compared to both mouse and rat. Fibulin 2 is considered a multifunctional binding protein due to its association with numerous ECM components, but its specific interactions have yet to be determined. Fibulin 2 is localized at the interface between microfibrils and the elastin core and its known interactions include nidogen-1, perlecan, laminin, aggrecan, endostatins, versican, collagen, and tropoelastin. It is down-regulated in numerous forms of cancer including breast, colorectal, lung, esophageal, and squamous cell carcinoma, but over-expression has been shown with solid tumors. There is also evidence that suggests that Fibulin 2 may play an indirect role in the neurogenesis of adult neural stem cells via interaction with integrins and TGF-beta 1.
- 分子量
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Calculated MW: 130.13 kDa
Observed MW: 130 kDa
- UniProt
- P98095
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