Glucuronidase beta Protein (AA 1-651) (His tag)
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- 抗原 See all Glucuronidase beta (GUSB) 蛋白
- Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-651
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Glucuronidase beta protein is labelled with His tag.
- 序列
- Met1-Thr651
- 产品特性
- A DNA sequence encoding the Human GUSβ protein (P08236) (Met1-Thr651) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GUSB 蛋白
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Glucuronidase, beta (GUSB) (AA 22-651) protein (GST tag)
GUSB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Glucuronidase, beta (GUSB) proteinGUSB 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
Glucuronidase, beta (GUSB) proteinGUSB 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
Glucuronidase, beta (GUSB) (AA 23-651) (Active) protein (His tag)GUSB 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))
- 别名
- Beta-glucuronidase (GUSB 产品)
- 别名
- GUSB Protein, beta-GUS Protein, gus Protein, BG Protein, MPS7 Protein, AI747421 Protein, Gur Protein, Gus Protein, Gus-r Protein, Gus-s Protein, Gus-t Protein, Gus-u Protein, Gut Protein, asd Protein, g Protein, Ac2-223 Protein, si:ch211-160e1.7 Protein, si:ct573103.7 Protein, glucuronidase beta Protein, beta-D-glucuronidase Protein, beta-glucuronidase Protein, beta glucuronidase Protein, glucuronidase, beta Protein, GUSB Protein, bglR Protein, SSO_RS14735 Protein, Glu Protein, Gusb Protein, gusb Protein
- 背景
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Abbreviation: Beta-glucuronidase,GUSB
Target Synonym: Beta-glucuronidase,EC 3.2.1.31,Beta-G1,GUSB
Background: Human beta -Glucuronidase (EC 3.2.1.31) encoded by the GUSB gene is a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans that include heparan sulfate, chondroitin sulfate and hyaluronan. The enzyme is only active on the glucuronic acid of the non-reducing end. The native protein has been reported as a tetrameric glycoprotein composed of identical subunits. Mutations in the GUSB gene are linked to mucopolysaccharidosis type VII. Accumulation of partially degraded glycosaminoglycans, with glucuronic acid residues at the non-reducing termini, are usually found in the lysosomes of patients with the disease. It has also been reported that this enzyme may contribute to the depletion of chondroitin from cartilage and thereby facilitate the damage of joints in rheumatoid arthritis.
- 分子量
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Calculated MW: 71.5 kDa
Observed MW: 80 kDa
- UniProt
- P08236
- 途径
- Glycosaminoglycan Metabolic Process
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