FLT1 Protein (AA 1-328) (His tag)
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- 抗原 See all FLT1 蛋白
- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-328
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FLT1 protein is labelled with His tag.
- 序列
- Met1-Ile328
- 产品特性
- A DNA sequence encoding the Human VEGFR-1 protein (P17948) (Met1-Ile328) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FLT1 蛋白
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Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 27-756) protein (His-Avi Tag)
FLT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) protein (His-Avi Tag,Biotin)FLT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 23-759) (Active) protein (Fc Tag)FLT1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 27-756) (Active) protein (His tag,AVI tag,Biotin)FLT1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 581-687) protein (GST tag)FLT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (Active) protein (His tag)FLT1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
- 别名
- VEGFR-1 (FLT1 产品)
- 别名
- FLT Protein, FLT-1 Protein, VEGFR-1 Protein, VEGFR1 Protein, FLT1 Protein, flt1b Protein, sFlt1 Protein, AI323757 Protein, Flt-1 Protein, fms related tyrosine kinase 1 Protein, FMS-related tyrosine kinase 1 Protein, vascular endothelial growth factor receptor 1 Protein, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) Protein, FMS-like tyrosine kinase 1 Protein, vascular endothelial growth factor receptor-1 Protein, FLT1 Protein, Flt1 Protein, CpipJ_CPIJ012087 Protein, flt1 Protein, FLT-1 Protein
- 背景
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Abbreviation: VEGFR-1
Target Synonym: Vascular endothelial growth factor receptor 1,VEGFR-1,Fms-like tyrosine kinase 1,FLT-1,Tyrosine-protein kinase FRT,Tyrosine-protein kinase receptor FLT,Vascular permeability factor receptor,FLT,FLT-1,VEGFR-1,VEGFR1
Background: Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / FLT1 is expressed mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR-1 / FLT1 is not expressed in tumor cell lines. VEGFR-1 / FLT1 is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis. EGF-induced angiogenesis requires inverse regulation of VEGFR-1 and VEGFR-2 in tumor-associated endothelial cells. VEGFR-1 / FLT1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
- 分子量
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Calculated MW: 35.97 kDa
Observed MW: 35 kDa
- UniProt
- P17948
- 途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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