IL-19 Protein (AA 1-177) (His tag)
-
- 抗原 See all IL-19 (IL19) 蛋白
- IL-19 (IL19) (Interleukin 19 (IL19))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-177
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This IL-19 protein is labelled with His tag.
- 序列
- Met1-Ala177
- 产品特性
- A DNA sequence encoding the Human IL-19 protein (Q9UHD0) (Met1-Ala177) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL19 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
-
- 抗原
- IL-19 (IL19) (Interleukin 19 (IL19))
- 别名
- IL-19 (IL19 产品)
- 别名
- IL-10C Protein, MDA1 Protein, NG.1 Protein, ZMDA1 Protein, IL19 Protein, interleukin 19 Protein, IL19 Protein, Il19 Protein
- 背景
-
Abbreviation: IL-19
Target Synonym: IL-10C,Interleukin-19,MDA1,NG.1,ZMDA1
Background: The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the epithelial barrier with dextran sodium sulfate leads to increased IL-19 expression. Attenuated colitis in IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. Microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease.
- 分子量
-
Calculated MW: 19.36 kDa
Observed MW: 30 kDa
- UniProt
- Q9UHD0
-