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IL-19 Protein (AA 1-177) (His tag)

IL19 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505641
发货至: 中国
  • 抗原 See all IL-19 (IL19) 蛋白
    IL-19 (IL19) (Interleukin 19 (IL19))
    蛋白类型
    Recombinant
    产品特性
    AA 1-177
    宿主
    • 9
    • 4
    • 2
    资源
    • 9
    • 2
    • 2
    • 2
    HEK-293 Cells
    标记
    This IL-19 protein is labelled with His tag.
    序列
    Met1-Ala177
    产品特性
    A DNA sequence encoding the Human IL-19 protein (Q9UHD0) (Met1-Ala177) was expressed with a C-His.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product IL19 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    IL-19 (IL19) (Interleukin 19 (IL19))
    别名
    IL-19 (IL19 产品)
    别名
    IL-10C Protein, MDA1 Protein, NG.1 Protein, ZMDA1 Protein, IL19 Protein, interleukin 19 Protein, IL19 Protein, Il19 Protein
    背景

    Abbreviation: IL-19

    Target Synonym: IL-10C,Interleukin-19,MDA1,NG.1,ZMDA1

    Background: The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the epithelial barrier with dextran sodium sulfate leads to increased IL-19 expression. Attenuated colitis in IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. Microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease.

    分子量

    Calculated MW: 19.36 kDa

    Observed MW: 30 kDa

    UniProt
    Q9UHD0
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