Calnexin Protein (CANX) (AA 1-481) (His tag)
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- 抗原 See all Calnexin (CANX) 蛋白
- Calnexin (CANX)
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-481
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Calnexin protein is labelled with His tag.
- 序列
- Met1-Pro481
- 产品特性
- A DNA sequence encoding the Human CANX protein (P27824) (Met1-Pro481) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CANX 蛋白
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Calnexin (CANX) (AA 504-592) protein (GST tag)
CANX 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Calnexin (CANX)
- 别名
- Calnexin (CANX 产品)
- 别名
- CNX Protein, IP90 Protein, P90 Protein, 1110069N15Rik Protein, AI988026 Protein, Cnx Protein, D11Ertd153e Protein, canx Protein, clgn Protein, clnx Protein, cnx Protein, PP90 Protein, zgc:63524 Protein, wu:fe06b12 Protein, CANX Protein, calnexin Protein, CalNeXin Protein, calnexin L homeolog Protein, CANX Protein, Canx Protein, cnx-1 Protein, canx.L Protein, canx Protein, LOC100283947 Protein
- 背景
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Abbreviation: Calnexin,CANX
Target Synonym: Calnexin,IP90,Major Histocompatibility Complex Class I Antigen-Binding Protein p88,p90,CANX
Background: Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.
- 分子量
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Calculated MW: 52.8 kDa
Observed MW: 60 kDa
- UniProt
- P27824
- 途径
- MAPK Pathway, Thyroid Hormone Synthesis
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