LPA Protein (AA 1719-2038) (His tag)
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- 抗原 See all LPA (APOA) 蛋白
- LPA (APOA) (Apolipoprotein A (APOA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1719-2038
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LPA protein is labelled with His tag.
- 序列
- Asp1719-Arg2038
- 产品特性
- A DNA sequence encoding the Human LP-a protein (P08519) (Asp1719-Arg2038) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product APOA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- LPA (APOA) (Apolipoprotein A (APOA))
- 别名
- Lipoprotein A (APOA 产品)
- 别名
- AK38 Protein, APOA Protein, LP Protein, Apo(a) Protein, Lp(a) Protein, lipoprotein(a) Protein, LPA Protein
- 背景
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Abbreviation: Apolipoprotein,Lp
Target Synonym: APOA,Apolipoprotein(a),Apo(a),Lp(a),LPA,Lp(a)
Background: Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-Lp(a). Apo(a) fragments accumulate in atherosclerotic lesions, where they may promote thrombogenesis. O-glycosylation may limit the extent of proteolytic fragmentation. Homology with plasminogen kringles IV and V is thought to underlie the atherogenicity of the protein, because the fragments are competing with plasminogen for fibrin(ogen) binding.
- 分子量
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Calculated MW: 35.09 kDa
Observed MW: 35 kDa
- UniProt
- P08519
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