Frataxin Protein (FXN) (AA 42-210) (His tag)
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- 抗原 See all Frataxin (FXN) 蛋白
- Frataxin (FXN)
- 蛋白类型
- Recombinant
- 产品特性
- AA 42-210
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Frataxin protein is labelled with His tag.
- 序列
- Leu42-Ala210
- 产品特性
- A DNA sequence encoding the Human FXN protein (Q16595) (Leu42-Ala210) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FXN 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Frataxin (FXN)
- 别名
- Frataxin (FXN 产品)
- 别名
- zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein
- 背景
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Abbreviation: Frataxin,FXN
Target Synonym: Frataxin,mitochondrial,Friedreich ataxia protein,FXN,FRDA,X25,Frataxin intermediate form
Background: Frataxin intermediate form can cleave by mitochondrial processing peptidase(MPP) to the mature frataxin. Frataxin is a nuclear-encoded mitochondrial protein highly conserved in prokaryotes and eukaryotes. Its deficiency was initially described as the phenotype of Friedreich's ataxia, an autosomal recessive disease in humans. Although several functions have been described for frataxin, that is, involvement in Fe-S cluster and heme synthesis, energy conversion and oxidative phosphorylation, iron handling and response to oxidative damage, its precise function remains unclear. Although there is a general consensus on the participation of frataxin in the maintenance of cellular iron homeostasis and in iron metabolism, this protein may have other specific functions in different tissues and organisms.
- 分子量
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Calculated MW: 18.48 kDa
Observed MW: 21 kDa
- UniProt
- Q16595
- 途径
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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