FGF18 Protein (AA 1-207) (His tag)
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- 抗原 See all FGF18 蛋白
- FGF18 (Fibroblast Growth Factor 18 (FGF18))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-207
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FGF18 protein is labelled with His tag.
- 序列
- Met1-Ala207
- 产品特性
- A DNA sequence encoding the Human FGF18 protein (O76093) (Met1-Ala207) was expressed with a C-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FGF18 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- FGF18 (Fibroblast Growth Factor 18 (FGF18))
- 别名
- FGF-18 (FGF18 产品)
- 别名
- FGF-18 Protein, ZFGF5 Protein, D130055P09Rik Protein, fgf18 Protein, FGF18 Protein, fgf18l Protein, fibroblast growth factor 18 Protein, fibroblast growth factor 18a Protein, fibroblast growth factor 18b Protein, FGF18 Protein, Fgf18 Protein, fgf18a Protein, Tsp_09844 Protein, fgf18b Protein
- 背景
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Abbreviation: FGF-18
Target Synonym: Fibroblast growth factor 18,FGF-18,zFGF5,FGF18,UNQ420,PRO856
Background: Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that FGF18 is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Experiment datas identified FGF18 as a selective ligand for FGFR3 in limb bud mesenchymal cells, which suppressed proliferation and promoted their differentiation and production of cartilage matrix. FGF18 appears to regulate cell proliferation and differentiation positively in osteogenesis and negatively in chondrogenesis.
- 分子量
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Calculated MW: 22.66 kDa
Observed MW: 32 kDa
- UniProt
- O76093
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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