BDNF Protein (AA 1-247) (His tag)
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- 抗原 See all BDNF 蛋白
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-247
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This BDNF protein is labelled with His tag.
- 序列
- Met1-Arg247
- 产品特性
- A DNA sequence encoding theHuman BDNF protein (P23560) (Met1-Arg247) was expressed with a C-His.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BDNF 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- 别名
- BDNF (BDNF 产品)
- 别名
- ANON2 Protein, BULN2 Protein, bdnf-A Protein, BDNF Protein, bdnf Protein, brain derived neurotrophic factor Protein, brain-derived neurotrophic factor Protein, brain-derived neurotrophic factor L homeolog Protein, brain-derived neurotrophic factor S homeolog Protein, BDNF Protein, Bdnf Protein, bdnf Protein, bdnf.L Protein, bdnf.S Protein
- 背景
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Abbreviation: BDNF
Target Synonym: Abrineurin,ProBDNF
Background: Important signaling molecule that activates signaling cascades downstream of NTRK2.During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
- 分子量
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Calculated MW: 26 kDa
Observed MW: 26 kDa
- UniProt
- P23560
- 途径
- RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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