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LILRA5 Protein (AA 42-268) (His tag)

LILRA5 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505590
发货至: 中国
  • 抗原 See all LILRA5 蛋白
    LILRA5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5 (LILRA5))
    蛋白类型
    Recombinant
    产品特性
    AA 42-268
    宿主
    • 11
    • 2
    资源
    • 7
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This LILRA5 protein is labelled with His tag.
    序列
    Gly42-Arg268
    产品特性
    Recombinant Human LILRA5 Member 5 is produced by our Mammalian expression system and the target gene encoding Gly42-Arg268 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    <1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product LILRA5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    LILRA5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5 (LILRA5))
    别名
    LILRA5 (LILRA5 产品)
    别名
    CD85 Protein, CD85F Protein, ILT-11 Protein, ILT11 Protein, LILRB7 Protein, LIR-9 Protein, LIR9 Protein, E030017K20 Protein, EG232801 Protein, Gm4878 Protein, Lilrc1 Protein, leukocyte immunoglobulin like receptor A5 Protein, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 Protein, LILRA5 Protein, Lilra5 Protein
    背景

    Abbreviation: LILRA5

    Target Synonym: Leukocyte immunoglobulin-like receptor subfamily A member 5,CD85 antigen-like family member F,Immunoglobulin-like transcript 11,ILT-11,Leukocyte immunoglobulin-like receptor 9,LIR-9,CD85f,LILRA5,LILRB7,CD85F,ILT11,LILRB7,LIR-9,LIR9

    Background: Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5(LILRA5)is a member of the leukocyte immunoglobulin-like receptors (LILR), comprise a family of activating and inhibitory type immunoreceptors. LILRA5 consists of a 227 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 10 aa cytoplasmic tail. The ECD contains two Ig-like domains and the transmembrane segment contains a positively charged aspartic acid residue which may mediate its association with the signaling molecule, FcR common gamma chain. LILRA5 is expressed by monocytes, macrophages, and neutrophils. Cross-linking of LILRA5 on monocytes induces the expression of pro-inflammatory cytokines (IL-1beta, IL-6, TNF-alpha) as well as the anti-inflammatory IL-10. It can be detected in tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.

    分子量

    Calculated MW: 26.1 kDa

    Observed MW: 35-40 kDa

    UniProt
    A6NI73
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