CD22 Protein (AA 24-331) (His tag)
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- 抗原 See all CD22 蛋白
- CD22 (CD22 Molecule (CD22))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-331
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宿主
- 大鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This CD22 protein is labelled with His tag.
- 序列
- Trp 24-Thr 331
- 产品特性
- A DNA sequence encoding the Rat CD22/Siglec-2 protein (D3ZD88) (Trp 24-Thr 331) was expressed with N-His.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CD22 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- CD22 (CD22 Molecule (CD22))
- 别名
- CD22 (CD22 产品)
- 别名
- A530093D23 Protein, Lyb-8 Protein, Lyb8 Protein, SIGLEC-2 Protein, SIGLEC2 Protein, siglec-2 Protein, CD22 antigen Protein, CD22 molecule Protein, Cd22 Protein, CD22 Protein
- 背景
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Abbreviation: CD22,Siglec-2
Target Synonym: CD22 antigen,Cd22,
Background: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
- 分子量
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Calculated MW: 33.77 kDa
Observed MW: 39 kDa
- UniProt
- D3ZD88
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