TGFB2 Protein (AA 331-442) (His tag)
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- 抗原 See all TGFB2 蛋白
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 331-442
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宿主
- 大鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This TGFB2 protein is labelled with His tag.
- 序列
- Ala 331-Ser 442
- 产品特性
- A DNA sequence encoding the Rat TGF-beta 2/TGFB2 protein (Q07257) (Ala 331-Ser 442) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product TGFB2 蛋白
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Transforming Growth Factor, beta 2 (TGFB2) protein (His tag)
TGFB2 宿主: 人 宿主: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS-PAGE gel WB, Imm, ELISA, STD
Transforming Growth Factor, beta 2 (TGFB2) (AA 303-414) proteinTGFB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 2 (TGFB2) (AA 303-414) protein (AVI tag,Biotin)TGFB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 2 (TGFB2) (AA 1-414) protein (GST tag)TGFB2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Transforming Growth Factor, beta 2 (TGFB2) (Active) proteinTGFB2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
- 别名
- TGF-beta 2 (TGFB2 产品)
- 别名
- LDS4 Protein, TGF-beta2 Protein, tgf-beta2 Protein, tgfb2-A Protein, BB105277 Protein, Tgf-beta2 Protein, Tgfb-2 Protein, TGF-beta 2 Protein, Tgfbr2T Protein, TGFB2 Protein, TGFbeta2 Protein, MGF Protein, TGF-B2 Protein, transforming growth factor beta 2 Protein, transforming growth factor beta 2 L homeolog Protein, transforming growth factor, beta 2 Protein, transforming growth factor, beta receptor 2 Protein, TGFB2 Protein, tgfb2.L Protein, Tgfb2 Protein, Tgfbr2 Protein, tgfb2 Protein
- 背景
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Abbreviation: TGF-beta 2,TGFB2
Target Synonym: BSC-1 cell growth inhibitor,cetermin,Glioblastoma-derived T-cell suppressor factor,G-TSF,polyergin,transforming growth factor beta-2
Background: TGF-beta 2 (transforming growth factor beta 2) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cysteine knot structure. TGF-beta 1, -2 and -3 are highly pleiotropic cytokines proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition. Each TGF-beta isoform has some non-redundant functions, for TGF-beta 2, mice with targeted deletion show defects in development of cardiac, lung, craniofacial, limb, eye, ear and urogenital systems. Covalent linkage of LAP to one of three latent TGF-beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix. TGF-beta is activated from latency by pathways that include actions of the protease plasmin, matrix metalloproteases, thrombospondin 1 and a subset of integrins. TGF-beta 2 signaling begins with binding to a complex of the accessory receptor betaglycan (also known as TGF-beta RIII) and a type II ser/thr kinase receptor termed TGF-beta RII. This receptor then phosphorylates and activates another ser/thr kinase receptor, TGF-beta RI (also called activin receptor-like kinase (ALK) -5), or alternatively, ALK-1. The whole complex phosphorylates and activates Smad proteins that regulate transcription. Use of other signaling pathways that are Smad-independent allows for disparate actions observed in response to TGF-beta in different contexts.
- 分子量
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Calculated MW: 12.21 kDa
Observed MW: 13 kDa
- UniProt
- Q07257
- 途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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