TGFB3 Protein (AA 24-412) (His tag)
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- 抗原 See all TGFB3 蛋白
- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-412
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宿主
- 大鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This TGFB3 protein is labelled with His tag.
- 序列
- Leu 24-Ser 412
- 产品特性
- A DNA sequence encoding the Rat TGF-beta 3/TGFB3 protein (Q07258) (Leu 24-Ser 412) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product TGFB3 蛋白
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Transforming Growth Factor, beta 3 (TGFB3) (AA 301-412) protein
TGFB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 3 (TGFB3) (AA 301-412) protein (AVI tag,Biotin)TGFB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 3 (TGFB3) (Active) proteinTGFB3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Transforming Growth Factor, beta 3 (TGFB3) (AA 1-412) protein (GST tag)TGFB3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
- 别名
- TGF-beta 3 (TGFB3 产品)
- 别名
- TGFB3 Protein, ARVD Protein, TGF-beta3 Protein, Tgfb-3 Protein, TGF-B3 Protein, TGFbeta3 Protein, wu:fc78g09 Protein, zgc:92058 Protein, transforming growth factor beta 3 Protein, transforming growth factor, beta 3 Protein, TGFB3 Protein, Tgfb3 Protein, tgfb3 Protein
- 背景
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Abbreviation: TGF-beta 3,TGFB3
Target Synonym: ARVD,ARVD1,LDS5,RNHF,TGFbeta 3,transforming growth factor beta-3
Background: TGF?-beta 3 (transforming growth factor-beta 3) is a member of a TGF?-beta superfamily subgroup that is defined by their structural and functional similarities. TGF-beta 3 and its closely related proteins, TGF-beta 1 and ? beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial-?mesenchymal transition. The non-redundant biological effects of TGF-? beta 3 include involvement in palatogenesis, chondrogenesis, and pulmonary development. Rat TGF?-beta 3 cDNA encodes a 412 amino acid (aa) precursor that contains a 23 aa signal peptide and a 389 aa proprotein. TGF-beta 3 is secreted as a latent complex. This latent form of TGF-beta 3 is activated by integrins, thrombospondin-1, plasmin, and matrix metalloproteases. It can also be activated by extreme pH and reactive oxygen species. TGF-beta 3 binds with high affinity to TGF-beta RII, a type II serine/threonine kinase receptor. This receptor then phosphorylates and activates type I serine/threonine kinase receptors, TGF-? beta RI or ALK-?1, to modulate transcription through Smad phosphorylation. The divergent biological effects exerted by individual TGF-beta isoforms is dependent upon the recruitment of co-receptors (TGF-? beta RIII and endoglin) and the subsequent initiation of Smad--dependent or -independent signaling pathways.
- 分子量
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Calculated MW: 42.68 kDa
Observed MW: 50 kDa
- UniProt
- Q07258
- 途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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