SERPINB2 Protein (AA 1-416) (His tag)
-
- 抗原 See all SERPINB2 蛋白
- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-416
-
宿主
- 大鼠
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This SERPINB2 protein is labelled with His tag.
- 序列
- Met 1-Pro 416
- 产品特性
- A DNA sequence encoding the Rat PAI-2 protein (P29524) (Met 1-Pro 416) was expressed with N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SERPINB2 蛋白
-
Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) protein (GST tag)
SERPINB2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-100) protein (GST tag)SERPINB2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
-
- 抗原
- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
- 别名
- PAI-2 (SERPINB2 产品)
- 别名
- HsT1201 Protein, PAI Protein, PAI-2 Protein, PAI2 Protein, PLANH2 Protein, SERPINB2 Protein, Planh2 Protein, ovalbumin Protein, Pai2a Protein, serpin family B member 2 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 2 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 2 Protein, SERPINB2 Protein, Serpinb2 Protein
- 物质类
- Amino Acid
- 背景
-
Abbreviation: PAI-2
Target Synonym: HsT1201;PAI;PAI-2;PAI2;PLANH2
Background: Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. SerpinB2, also known as Plasminogen activator inhibitor 2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor and PAI2, is a cytoplasm protein which belongs to the serpin family and Ov-serpin subfamily. SerpinB2 is a major product of activated monocytes and macrophages and is substantially induced during most inflammatory processes. Distinct from its widely described extracellular role as an inhibitor of urokinase plasminogen activator. SerpinB2 has been shown to have an intracellular role as a retinoblastoma protein (Rb)-binding protein that inhibits Rb degradation. SerpinB2 is widely described as an inhibitor of urokinase plasminogen activator. SerpinB2 inhibits urokinase-type plasminogen activator. The monocyte derived SerpinB2 is distinct from the endothelial cell-derived PAI-1. SerpinB2 is a potentially important inducible host factor that significantly promotes HIV-1 replication.
- 分子量
-
Calculated MW: 45.65 kDa
Observed MW: 45 kDa
- UniProt
- P29524
- 途径
- Autophagy
-
